Awards & Honors
Award | Conferred By | Date |
---|---|---|
Y.S. Chow Distinguished Lecture Award | Chinese Institute of Probability and Statistics | 2022 |
Elected Fellow | American Statistical Association | 2018 |
Distinguished Alumni Award | National Tainan Girls' Senior High School, Tainan, Taiwan | 2017 |
NIH Merit Award | National Institute of Allergy and Infectious Diseases, Bethesda, MD | 2007 |
Margaret Merrell Award | Department of Biostatistics, Johns Hopkins University, Baltimore, MD | 2002 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
Johns Hopkins University | Adjunct Professor | 2018 | |
University of California | Professor | 2017 | |
Johns Hopkins University | Associate Professor | 2013 | |
National Institute of Allergy and Infectious Diseases, NIH | Mathematical Statistician | 2004 | |
Johns Hopkins University | PhD | Biostatistics | 2002 |
University of Minnesota | Assistant Professor | 2002 | |
National Tsing-Hua University | MS | Mathematics | 1996 |
National Tsing-Hua University | BS | Mathematics | 1994 |
Program Affiliations
World Health Organization
Cameroon’s Ministry of Health
Center for Global Surgical Studies
Grants and Funding
- Improving causal inference in Alzheimer's Disease prevention research on modifiable risk factors: the Triangulation of Innovative Methods to End AD (TIME-AD) project | NIH/NIA | 2024-09-01 - 2029-08-31 | Role: Co-leader of Analytics Core
- Cancer Center Support Grant – Biostatistics & Population Research Shared Resource | NIH/NCI | 2023-09-01 - 2028-05-31 | Role: Co-Investigator
- The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation | NIH/NHLBI | 2022-08-01 - 2027-07-31 | Role: Co-Investigator
- CF Statistical Expertise and Network (CF StatNet) Award | Cystic Fibrosis Foundation | 2022-09-01 - 2025-08-31 | Role: Statistician
- Mixed Data Meta-analysis: Integration of Individual Participant and Aggregate Data | PCORI | 2021-11-01 - 2025-01-31 | Role: Co-Investigator
- Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation | NIH | 2018-06-15 - 2023-05-31 | Role: Co-Investigator
- UCSF Liver Core Center, Biostatistics Core | NIH/NIDDK | 2018-06-01 - 2023-05-31 | Role: Statistician
- Cancer Center Support Grant | NIH | 1999-08-05 - 2023-05-31 | Role: Co-Investigator
- Allergy, Immunology and Transplantation Research (UCSF Coordinating Center) | NIH/NIAID | 2021-09-01 - 2023-01-31 | Role: Statistician
- A novel natural history study of medullary thyroid carcinoma | University of Texas M.D. Anderson Cancer Center | 2019-09-01 - 2022-07-31 | Role: Statistician
- Statistical Methods for Survival and Recurrent Event Data in Clinical Research | NIH | 2015-07-01 - 2021-06-30 | Role: Principal Investigator
- Reprogramming the pancreatic tumor microenvironment with immunotherapy | NIH/NCI | 2015-07-01 - 2020-06-30 | Role: Statistician/Principal Investigator (Subaward)
- Comparing Patient Centered Outcomes in the Management of Pain between Emergency Departments and Dedicated Acute Care Facilities for Adults with Sickle Cell disease | PCORI | 2017-09-01 - 2018-12-31 | Role: Statistician/Principal Investigator (Subaward)
Research Interests
Violence and Injury Prevention
Management of Health Services
Strengthening Health Systems
Positioning Injury Prevention as a Priority Area in the National Health Agenda
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 181
- Distribution-free prediction intervals under covariate shift, with an application to causal inference| | UCSF Research Profile
- Sequential data integration under dataset shift| | UCSF Research Profile
- Evaluating the positive predictive value of code-based identification of cirrhosis and its complications utilizing GPT-4.| | PubMed
- The Multi-Institutional Medullary Thyroid Cancer Collaborative Registry: Can a Rare Tumor Registry Accurately Represent the Real-World Patient Population?| | PubMed
- Liver transplantation provides survival benefit at all levels of frailty: From the Multicenter Functional Assessment in Liver Transplantation Study.| | PubMed
- The Liver Frailty Index enhances mortality risk prediction above and beyond MELD 3.0 alone.| | PubMed
- Scalable estimation for high velocity survival data able to accommodate adding covariates| | UCSF Research Profile
- Clinically relevant cut-points for changes in the Liver Frailty Index are associated with waitlist mortality in patients with cirrhosis.| | PubMed
- The burden of significant pain in the cirrhosis population: Risk factors, analgesic use, and impact on health care utilization and clinical outcomes.| | PubMed
- Salvage therapies including retreatment with BCMA-directed approaches after BCMA CAR-T relapses for multiple myeloma.| | PubMed
- Efficient data integration under prior probability shift.| | PubMed
- A modified Hospital Frailty Risk Score for patients with cirrhosis undergoing abdominal operations.| | PubMed
- Disturbed sleep after lung transplantation is associated with worse patient-reported outcomes and chronic lung allograft dysfunction.| | PubMed
- Time to be blunt: Substance use in cystic fibrosis.| | PubMed
- Assessing Adherence to US LI-RADS Follow-up Recommendations in Vulnerable Patients Undergoing Hepatocellular Carcinoma Surveillance.| | PubMed
- The liver frailty index is a predictor of healthcare utilization after liver transplantation in older adults.| | PubMed
- Neighborhood Income Is Associated with Health Care Use in Pediatric Short Bowel Syndrome.| | PubMed
- Fatty Liver Education Promotes Physical Activity in Vulnerable Groups, Including Those With Unhealthy Alcohol Use.| | PubMed
- Simultaneous selection and incorporation of consistent external aggregate information.| | PubMed
- Association of state Medicaid expansion policies with pediatric liver transplant outcomes.| | PubMed
- Randomized phase 2 study of digital life coaching during transplantation for myeloma.| | PubMed
- Variation in skeletal muscle mass among patients with cirrhosis of different self-identified race/ethnicity.| | PubMed
- Correlation of SUV on Early Interim PET with Recurrence-Free Survival and Overall Survival in Primary Operable HER2-Positive Breast Cancer (the TBCRC026 Trial).| | PubMed
- Impact of corticosteroids on efficacy of BCMA targeted CAR-T therapy in multiple myeloma.| | PubMed
- Ethnic differences in staphylococcus aureus acquisition in cystic fibrosis.| | PubMed
- Diabetes mellitus and risk of breast cancer: a large-scale, prospective, population-based study.| | PubMed
- Hypoxia-specific imaging in patients with lymphoma undergoing CAR-T therapy.| | PubMed
- The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation.| | PubMed
- Clinical Characteristics Associated With Posttransplant Survival Among Adults 70 Years Old or Older Undergoing Liver Transplantation.| | PubMed
- Intensity of Cyclophosphamide-Based Bridging Therapy Before Chimeric Antigen Receptor T Cell Therapy in Myeloma.| | PubMed
- Steroid Avoidance After Adult Living Donor Liver Transplant: A Cohort Analysis.| | PubMed
- DYNAMIC RISK PREDICTION TRIGGERED BY INTERMEDIATE EVENTS USING SURVIVAL TREE ENSEMBLES.| | PubMed
- Significance of the pee-value: relevance of 24-hour urine studies for patients with myeloma.| | PubMed
- The tele-liver frailty index (TeLeFI): development of a novel frailty tool in patients with cirrhosis via telemedicine.| | PubMed
- Difficult or high risk? Objective task assessment vs. faculty perceptions of surgical skills| | UCSF Research Profile
- Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis.| | PubMed
- Safety and Efficacy of BCMA CAR-T Cell Therapy in Older Patients With Multiple Myeloma.| | PubMed
- Cytomegalovirus seropositivity is associated with improved responses to CD38 monoclonal antibody therapies in multiple myeloma: A single-centre retrospective study.| | PubMed
- Women with cirrhosis have lower self-rated health than men.| | PubMed
- Association of Frailty With Health-Related Quality of Life in Liver Transplant Recipients.| | PubMed
- Regression Modeling for Recurrent Events Possibly with an Informative Terminal Event Using R Package reReg.| | PubMed
- CT-quantified sarcopenic visceral obesity is associated with poor transplant waitlist mortality in patients with cirrhosis.| | PubMed
- Improved semiparametric estimation of the proportional rate model with recurrent event data.| | PubMed
- Semiparametric estimation of the transformation model by leveraging external aggregate data in the presence of population heterogeneity.| | PubMed
- Maximum Likelihood Estimation for Shape-restricted Single-index Hazard Models.| | PubMed
- Inflammatory bowel disease type influences development of elevated liver enzymes.| | PubMed
- Assessment of Surgeon Performance of Advanced Open Surgical Skills Using a Microskills-Based Novel Curriculum.| | PubMed
- Antibody and T-cell responses by ultra-deep T-cell receptor immunosequencing after COVID-19 vaccination in patients with plasma cell dyscrasias.| | PubMed
- Endocrine surgeons are performing more thyroid lobectomies for low-risk differentiated thyroid cancer since the 2015 ATA guidelines.| | PubMed
- Association of a Dominant T-Cell Clone in Peripheral Blood With Time to Systemic Treatment in Patients With Stage IB Mycosis Fungoides.| | PubMed
- Sarcopenic visceral obesity is associated with increased post-liver transplant mortality in acutely ill patients with cirrhosis.| | PubMed
- Analysis of a SARS-CoV-2 convalescent cohort identified a common strategy for escape of vaccine-induced anti-RBD antibodies by Beta and Omicron variants.| | PubMed
- Infectious complications in patients with relapsed refractory multiple myeloma after BCMA CAR T-cell therapy.| | PubMed
- BivRec: an R package for the nonparametric and semiparametric analysis of bivariate alternating recurrent events.| | PubMed
- Association of Primary Care Shortage Areas with Adverse Outcomes after Pediatric Liver Transplant.| | PubMed
- Consent to organ offers from public health service "Increased Risk" donors decreases time to transplant and waitlist mortality.| | PubMed
- Digital Life Coaching During Stem Cell Transplantation: Development and Usability Study.| | PubMed
- Geriatric assessment in adults age 50 years and older undergoing autologous hematopoietic cell transplantation for lymphoma.| | PubMed
- Patterns and Predictors of Functional Decline after Allogeneic Hematopoietic Cell Transplantation in Older Adults.| | PubMed
- Association between exposure to radioactive iodine after the Chernobyl accident and thyroid volume in Belarus 10-15 years later.| | PubMed
- Frailty, mortality, and health care utilization after liver transplantation: From the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.| | PubMed
- Outcomes of SOT Recipients With COVID-19 in Different Eras of COVID-19 Therapeutics.| | PubMed
- Macrophage activation syndrome-like (MAS-L) manifestations following BCMA-directed CAR T cells in multiple myeloma.| | PubMed
- The Impact of Median Model for End-Stage Liver Disease at Transplant Minus 3 National Policy on Waitlist Outcomes in Patients With and Without Hepatocellular Carcinoma.| | PubMed
- Early Dynamics and Depth of Response in Multiple Myeloma Patients Treated With BCMA CAR-T Cells.| | PubMed
- Evaluation of subcutaneous daratumumab injections in the ambulatory care setting.| | PubMed
- Triangulating Evidence to Infer Pathways that Influence Ebola Virus Disease-Related Stigma and Clinical Findings among Survivors: An Observational Cohort Study.| | PubMed
- Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates.| | PubMed
- Cholesterol lowering drug use and breast cancer survival: the Multiethnic Cohort Study.| | PubMed
- Additive rates model for recurrent event data with intermittently observed time-dependent covariates.| | PubMed
- Treatment of Acute Pain in Adults With Sickle Cell Disease in an Infusion Center Versus the Emergency Department : A Multicenter Prospective Cohort Study.| | PubMed
- Accuracy of the Lymph Node Yield in Surgery for Papillary Thyroid Cancer in Children.| | PubMed
- Synthesizing external aggregated information in the penalized Cox regression under population heterogeneity.| | PubMed
- Updated Results of TBCRC026: Phase II Trial Correlating Standardized Uptake Value With Pathological Complete Response to Pertuzumab and Trastuzumab in Breast Cancer.| | PubMed
- Phase 1b trial of isatuximab, an anti-CD38 monoclonal antibody, in combination with carfilzomib as treatment of relapsed/refractory multiple myeloma.| | PubMed
- Early Time-to-Tocilizumab after B Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy in Myeloma.| | PubMed
- Center variation in long-term outcomes for socioeconomically deprived children.| | PubMed
- Statistical inference on shape and size indexes for counting processes.| | PubMed
- Synthesizing external aggregated information in the presence of population heterogeneity: A penalized empirical likelihood approach.| | PubMed
- Impact of Polypharmacy Prior to Allogeneic Hematopoietic Stem Cell Transplantation in Older Adults.| | PubMed
- Reduced anxiety and changes in amygdala network properties in adolescents with training for awareness, resilience, and action (TARA).| | PubMed
- Heterogeneous Individual Risk Modeling of Recurrent Events.| | PubMed
- Ofatumumab, Etoposide, and Cytarabine Intensive Mobilization Regimen in Patients with High-risk Relapsed/Refractory Diffuse Large B-Cell Lymphoma Undergoing Autologous Stem Cell Transplantation.| | PubMed
- Early acquisition and conversion of Pseudomonas aeruginosa in Hispanic youth with cystic fibrosis in the United States.| | PubMed
- Serial comprehensive geriatric and quality of life assessments in adults age ≥ 50 years undergoing autologous hematopoietic cell transplantation.| | PubMed
- Neural Correlates of Smartphone Dependence in Adolescents.| | PubMed
- Estimation of infection density and epidemic size of COVID-19 using the back-calculation algorithm.| | PubMed
- Recurrent Events Analysis With Data Collected at Informative Clinical Visits in Electronic Health Records.| | PubMed
- Synchronous Versus Metachronous Colorectal Liver Metastasis Yields Similar Survival in Modern Era.| | PubMed
- Clinical value of measurable residual disease testing for assessing depth, duration, and direction of response in multiple myeloma.| | PubMed
- Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.| | PubMed
- Genetic effect estimates in case-control studies when a continuous variable is omitted from the model| | UCSF Research Profile
- A unified approach for synthesizing population-level covariate effect information in semiparametric estimation with survival data.| | PubMed
- The Effects of a Remote-based Weight Loss Program on Adipocytokines, Metabolic Markers, and Telomere Length in Breast Cancer Survivors: the POWER-Remote Trial.| | PubMed
- A single-center retrospective cohort analysis of venetoclax in relapsed/refractory multiple myeloma.| | PubMed
- Generalized scale-change models for recurrent event processes under informative censoring.| | PubMed
- A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer.| | PubMed
- Censored linear regression in the presence or absence of auxiliary survival information.| | PubMed
- Case-control versus case-only estimates of gene-environment interactions with common and misclassified clinical diagnosis.| | PubMed
- Functional Status as Measured by Geriatric Assessment Predicts Inferior Survival in Older Allogeneic Hematopoietic Cell Transplantation Recipients.| | PubMed
- Application of machine learning to structural connectome to predict symptom reduction in depressed adolescents with cognitive behavioral therapy (CBT).| | PubMed
- Reply to E. Hindié et al.| | PubMed
- TBCRC026: Phase II Trial Correlating Standardized Uptake Value With Pathologic Complete Response to Pertuzumab and Trastuzumab in Breast Cancer.| | PubMed
- Limitation in Patient-Reported Function Is Associated with Inferior Survival in Older Adults Undergoing Autologous Hematopoietic Cell Transplantation.| | PubMed
- SEMIPARAMETRIC REGRESSION MODEL FOR RECURRENT BACTERIAL INFECTIONS AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION.| | PubMed
- Increased acute care utilization in a prospective cohort of adults with sickle cell disease.| | PubMed
- Semiparametric Regression Analysis of Panel Count Data: A Practical Review.| | PubMed
- Missing Information Principle: A Unified Approach for General Truncated and Censored Survival Data Problems.| | PubMed
- Streptococcal group A, C and G pharyngitis in school children: a prospective cohort study in Southern India.| | PubMed
- Semiparametric estimation of the accelerated mean model with panel count data under informative examination times.| | PubMed
- Sieve analysis using the number of infecting pathogens.| | PubMed
- Induced smoothing for rank-based regression with recurrent gap time data.| | PubMed
- Semiparametric regression analysis for alternating recurrent event data.| | PubMed
- Stromal Annexin A2 expression is predictive of decreased survival in pancreatic cancer.| | PubMed
- Estimation and Inference of Quantile Regression for Survival Data Under Biased Sampling.| | PubMed
- Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer.| | PubMed
- Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.| | PubMed
- Joint scale-change models for recurrent events and failure time.| | PubMed
- Nonparametric Benefit-Risk Assessment Using Marker Process in the Presence of a Terminal Event.| | PubMed
- Efficient Estimation of the Cox Model With Auxiliary Subgroup Survival Information.| | PubMed
- Who really gets strep sore throat? Confounding and effect modification of a time-varying exposure on recurrent events.| | PubMed
- Nonparametric analysis of bivariate gap time with competing risks.| | PubMed
- IGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicity.| | PubMed
- Recurrent event data analysis with intermittently observed time-varying covariates.| | PubMed
- Nonparametric methods for analyzing recurrent gap time data with application to infections after hematopoietic cell transplant.| | PubMed
- Plasmodium falciparum Gametocyte-Specific Antibody Profiling Reveals Boosting through Natural Infection and Identifies Potential Markers of Gametocyte Exposure.| | PubMed
- Impact of acute malaria on pre-existing antibodies to viral and vaccine antigens in mice and humans.| | PubMed
- Semiparametric likelihood inference for left-truncated and right-censored data.| | PubMed
- Incorporating founder virus information in vaccine field trials.| | PubMed
- Assessment of atherosclerosis in chronic granulomatous disease.| | PubMed
- Co-infection of long-term carriers of Plasmodium falciparum with Schistosoma haematobium enhances protection from febrile malaria: a prospective cohort study in Mali.| | PubMed
- Statistical inference methods for recurrent event processes with shape and size parameters.| | PubMed
- Parasite burden and severity of malaria in Tanzanian children.| | PubMed
- Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses.| | PubMed
- Combined estimating equation approaches for semiparametric transformation models with length-biased survival data.| | PubMed
- BCG vaccination in patients with severe combined immunodeficiency: complications, risks, and vaccination policies.| | PubMed
- Risk of cardiovascular adverse events from trastuzumab (Herceptin(®)) in elderly persons with breast cancer: a population-based study.| | PubMed
- Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria.| | PubMed
- B-cell activating factor (BAFF) is elevated in chronic granulomatous disease.| | PubMed
- The impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in mice.| | PubMed
- An intensive longitudinal cohort study of Malian children and adults reveals no evidence of acquired immunity to Plasmodium falciparum infection.| | PubMed
- Quantile regression for recurrent gap time data.| | PubMed
- Bevacizumab use and risk of cardiovascular adverse events among elderly patients with colorectal cancer receiving chemotherapy: a population-based study.| | PubMed
- Clinical characteristics and outcomes of influenza and other influenza-like illnesses in Mexico City.| | PubMed
- Semiparametric estimation for the additive hazards model with left-truncated and right-censored data.| | PubMed
- Composite Partial Likelihood Estimation Under Length-Biased Sampling, With Application to a Prevalent Cohort Study of Dementia.| | PubMed
- A maximum pseudo-profile likelihood estimator for the Cox model under length-biased sampling.| | PubMed
- Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen, F. tularensis LVS.| | PubMed
- Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes.| | PubMed
- Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies.| | PubMed
- Nonparametric estimation for length-biased and right-censored data.| | PubMed
- Analysis of recurrent gap time data using the weighted risk-set method and the modified within-cluster resampling method.| | PubMed
- Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice.| | PubMed
- A model checking method for the proportional hazards model with recurrent gap time data.| | PubMed
- Interferon-alpha produces significant decreases in HIV load.| | PubMed
- The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections.| | PubMed
- In vitro growth-inhibitory activity and malaria risk in a cohort study in mali.| | PubMed
- The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali.| | PubMed
- Safety and immunogenicity of multiple and higher doses of an inactivated influenza A/H5N1 vaccine.| | PubMed
- Semiparametric analysis for recurrent event data with time-dependent covariates and informative censoring.| | PubMed
- Antifungal activities of natural and synthetic iron chelators alone and in combination with azole and polyene antibiotics against Aspergillus fumigatus.| | PubMed
- The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals.| | PubMed
- Half- vs full-dose trivalent inactivated influenza vaccine (2004-2005): age, dose, and sex effects on immune responses.| | PubMed
- Sickle cell trait is associated with a delayed onset of malaria: implications for time-to-event analysis in clinical studies of malaria.| | PubMed
- CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients.| | PubMed
- Empirical Likelihood-Based Estimation of the Treatment Effect in a Pretest-Posttest Study.| | PubMed
- A comparison of various rate functions of a recurrent event process in the presence of a terminal event.| | PubMed
- The Statistical Analysis of Recurrent Events by COOK, R. J. and LAWLESS, J. F| | UCSF Research Profile
- Empirical likelihood‐based inference for genetic mixture models| | UCSF Research Profile
- Comparison of resource utilization and clinical outcomes between teaching and nonteaching medical services.| | PubMed
- Cryptococcosis and idiopathic CD4 lymphocytopenia.| | PubMed
- Monitoring rare serious adverse events from a new treatment and testing for a difference from historical controls.| | PubMed
- Analysing panel count data with informative observation times.| | PubMed
- Disciplinary action against physicians: who is likely to get disciplined?| | PubMed
- Nonparametric estimation of the bivariate recurrence time distribution.| | PubMed
- Kernel Estimation of Rate Function for Recurrent Event Data.| | PubMed
- Are transgender persons at higher risk for HIV than other sexual minorities? A comparison of HIV prevalence and risks| | UCSF Research Profile
- Joint Modeling and Estimation for Recurrent Event Processes and Failure Time Data.| | PubMed
- On stability of trimmed sums| | UCSF Research Profile
- Familial influence on age of onset among siblings with Huntington disease.| | PubMed
- A unified sampling approach for multipoint analysis of qualitative and quantitative traits in sib pairs.| | PubMed